I.v. injection of liposomes containing saturated PC was expected to increase LysoPC plasma levels by hydrolysis of liposomal PC in the systemic circulation by enzymes physiologically metabolising lipoproteins (endothelial lipase, LCAT) [41, 42], or after accumulation in the tumour tissue by phospholipase A2 secreted by the tumour cells [43, 44]. This evidence concerns the gene LIPG and neoplasm.