EFEMP1 and Familial drusen: Previous ocular genetic studies have identified a recurrent, missense mutation in exon-10 of EFEMP1 (c.1033C>T, p.R345W) associated with Doyne honeycomb retinal dystrophy (DHRD) and/or Malattia Leventinese (MLVT, MIM: 126600) in European and Asian families [11,20–24].