The overall survival rates for lung SCC and ADC patients with negative expression of Flot-2 protein were significantly higher than these with positive Flot-2 expression (P = 0.043, Fig 4A; P = 0.007, Fig 4D), as well as the overall survival rates for lung ADC patients with negative expression of EGFR were better than these with positive EGFR expression (P = 0.033, Fig 4E). Here, EGFR is linked to AIDS dementia complex.