NFKB1 and nasopharyngeal carcinoma: In the present hospital-based retrospective study, we found that the rs28362491ins ATTG variants of NFκB1 conferred an increased risk of NPC, and the rs696AA variant of IκBα contributed an increased risk of NPC by decreasing IκBα expression under the modulation of hsa-miR-449a but not hsa-miR-34b.