The percentage in the APS group significantly increased and reached normal levels on days 10 and 14 (P = 0.547 on day 10 and P = 0.431 on day 14vs. control group; P = 0.015 on day 10 and P = 0.007 on day 14vs. G-CSF group; Fig. 4). Here, CSF3 is linked to autoimmune polyendocrinopathy.