The chemotactic ability of mature BM granulocytes and peripheral blood PMNLs was higher in the APS group than in the CTX group (P < 0.001 on days 7, 10 and 14) and the G-CSF group (P < 0.001 on day 7, P = 0.001 on day 10 and P = 0.005 on day 14), particularly on days 10 and 14 after chemotherapy. The gene discussed is CSF3; the disease is autoimmune polyendocrinopathy.