Figure 2 summarizes the inflammasome formation steps. Mature IL-1β molecules induce expression of other cytokines. Secondary cytokines such as IL-6 recruit immune cells to the site of inflammation. There is a balance between the levels of activation and inhibition of inflammasome formation. Although IL-1β molecules help combat the infection, spontaneous or triggered overproduction of IL-1β causes adverse effects that are associated with inflammatory diseases such as FMF and CAPS. The gene discussed is IL1B; the disease is infection.