The ALDH1A1-high group was significantly associated with low serum levels of α-fetoprotein (AFP) (P = 0.0168), small tumor diameter (P = 0.0019), very little lymphovascular invasion (P = 0.0208), more differentiated pathology (P = 0.016) and good stage (P = 0.0215) (Table 1). This evidence concerns the gene AFP and neoplasm.