Multiple logistic regression analysis indicated that male sex, a younger age, the presence of hypertension, hypercholesterolemia, hypertriglyceridemia, low HDL-C levels, BMI ≥25 kg/m2, abdominal obesity, hyperuricemia, and the HtgW phenotype were independent predictors of an elevated ALT level. The gene discussed is GPT; the disease is hyperuricemia.