For all ischemic stroke, PRSs from 3 coagulation factors were significant: FVIIC% at inclusion thresholds P≤0.2 and 0.4 (most significant P=4.9×10−04); FX at inclusion threshold greater than P≤0.4 (most significant P=1.5×10−04); and FXIIIB for inclusion thresholds greater than P≤0.01 (most significant P=1.8×10−04). Here, F13B is linked to ischemic stroke.