For example, 17/22 tumours (in our discovery set Batch P) had a total of 61 ‘translocation breakpoints’ within a 1.4kb region at 29.065 Mb (reference genome GrCH37/hg19) on chromosome 22, within an intron of the TTC28 gene, up to seven in the same tumour, and the joined ‘breakpoints’ were all different. This evidence concerns the gene TTC28 and neoplasm.