Figure 3f shows the CD31 section of part of the tumor including both central and margin areas. Although the vascularity is not pronounced, it appears to be confined to the tumor borders (Fig. 3g–h and correspondingly colored boxes in Fig. 3f) primarily at the interface between the tumor and normal tissue. At the center, low vascularity is observed (Fig. 3i–j and corresponding boxes in Fig. 3f). This evidence concerns the gene PECAM1 and neoplasm.