Notably, two previous studies reported the SNPs rs12091564 and rs10218795 in the hemochromatosis type 2 gene (HFE2; also known as hemojuvelin [HJV]) to be associated with coronary artery disease (CAD) based on a two-marker association test and haplotype analysis [46, 47]. The gene discussed is HJV; the disease is coronary artery disorder.