The hazard ratio of 180-day mortality for severe sepsis patients with an elevated CRP/albumin ratio was 1.06 (95% CI, 1.03–1.10), that for an elevated SOFA score was 1.12 (95% CI, 1.07–1.180), that for advanced age was 1.02(95% CI, 1.01–1.03), and the ratio for patients with elevated lactate levels was 1.10 (95% CI, 1.05–1.14) (Table 2). The gene discussed is CRP; the disease is Sepsis.