With eRapa chow, there was a lower trend in the incidence of lymphoma in p53−/− mice but corresponding higher trend in the incidence of sarcomas (including leiomyoma, rhabdomyosarcoma, hemangiosarcoma and osteosarcoma); there was a similar but less pronounced trend in p53+/− mice. The gene discussed is TP53; the disease is leiomyoma.