Performing this task in ARepA allowed us to recover several genes already associated with NFκB and prostate cancer (Davis, Kucuk & Sarkar, 1999; Perkins, 2012), in addition to original findings including MEN1 as a novel putative upstream regulator (Bouwmeester et al., 2004; Hacker & Karin, 2006; Heppner et al., 2001; Wen et al., 2000) and ACBD6 as a potential downstream suppressor of NFκB-activation (Oberti et al., 2011; Pringle et al., 2012; Soupene et al., 2012; Wu et al., 2006). Here, ACBD6 is linked to Familial prostate cancer.