Pomegranate, and its juice, has received a great deal of attention related to potential chemo-protective effects, including beneficial effects in slowing of prostate-specific antigen (PSA) doubling time in men with prostate cancer (Pantuck et al., 2006; Pantuck et al., 2009; Paller et al., 2012). Here, KLK3 is linked to Familial prostate cancer.