NUCLEOLIN and breast cancer: From our screening experiment in MCF-7 cells, we were able to identify a previously validated breast cancer cell-specific protein DMPGTVLP that interacts with cell surface expressed nucleolin and increases the therapeutic effect of liposomal doxorubicin in vitro and in vivo by increasing the specific delivery of doxorubicin to MCF-7 cell nuclei (Wang et al., 2010a, 2014; Fagbohun et al., 2012).