Intestinal SLC26A3 mRNA has been reported to be downregulated in ulcerative colitis and in the IL10 transgenic colitis model (Yang et al., 1998; Lohi et al., 2002), but SLC26A3 protein levels in intestinal tissues of patients with ulcerative colitis were unchanged (Lohi et al., 2002). Here, SLC26A3 is linked to ulcerative colitis.