Intestinal SLC26A3 mRNA has been reported to be downregulated in ulcerative colitis and in the IL10 transgenic colitis model (Yang et al., 1998; Lohi et al., 2002), but SLC26A3 protein levels in intestinal tissues of patients with ulcerative colitis were unchanged (Lohi et al., 2002). This evidence concerns the gene IL10 and ulcerative colitis.