As demonstrated in Fig. 1, young PCOS women presented with a typical pattern of significantly elevated AMH and hyperandrogenism in comparison to young women with NFOR [TT 44.0 (95 % CI, 32.9 to 58.7) vs. 23.9 (95 % CI 20.3 to 28.1) ng/dL, (P < 0.05); AMH 7.7 (95 % CI 6.2 to 9.1) vs. 2.5 (95 % CI 2.0 to 3.0) ng/mL, (P < 0.05)]. The gene discussed is AMH; the disease is hyperandrogenism.