Immunohistochemistry staining for F4/80, a murine MΦ marker, in mouse BM showed that MM BM had a greater percentage of BM MΦs, similar to what we observed in human MM BM [3], and injection of CCL3 or CCL2 neutralizing antibodies significantly reduced the percentage of MΦs in murine MM BM (Figure 4E). The gene discussed is CCL3; the disease is Miyoshi myopathy.