Conversely, rs2075650 for the TOMM40/APOE locus revealed a p-value = 2.1 × 10−5 and OR = 1.65 (Table 5) implying that either this locus might be suggestive for the Italian FTD population or that there is an underlying presence of AD cases within our FTD cohort. Here, APOE is linked to Alzheimer disease.