These included Cell Cycle: G2/M DNA Damage Checkpoint Regulation, Cell Cycle Control of Chromosomal Replication, p53 Signaling, ATM Signaling, and Role of BRCA1 in DNA Damage Response etc. However, the HH CaCx cases appeared to be distinct from the LH cases in terms of genes and pathways associated with metastasis such as, Agranulocyte Adhesion and Diapedesis, Granulocyte Adhesion and Diapedesis, Glioma Invasiveness Signaling etc., which were not identified among LH cases. The gene discussed is ATM; the disease is central nervous system cancer.