In addition, the consumption of the HMUFA diet also down-regulated seven proteins involved in thrombus formation: prothrombin or coagulation factor II (F2), fibrinogen (FGB), alpha-fibrinogen precursor (FGA), Talin1 (TLN1) Gelsolin (GSN), Annexin2 (ANX2) and Capping protein (actin filament) muscle Z-line, beta (CAPZA1), which is especially important in MetS patients, as they are characterized by a pro-thrombotic state [36]. Here, ANXA2 is linked to metabolic syndrome.