MUC5AC and constipation disorder: Furthermore, after the AEtLP treatment, the mucosa thickness, the average muscle thickness, flat luminal surface thickness, mucin production, number of goblet cells and number of lieberkuhn crypts increased by more than 10.9–190% compared to the vehicle-treated constipation group, while the expression of muscarinic acetylcholine receptor (mAchR) decreased with 7.7–25%.