TNF and Shock: In the opposite case, the possible compensatory anti-inflammatory response syndrome results in immunoparalysis instead.24 Serum TNF-α and IL-6 levels of both groups herein significantly decreased after treatment (P<0.05), and the levels of the treatment group were significantly lower than those of the control group (P<0.05), indicating that Ringer’s sodium pyruvate solution inhibited the inflammatory response after septic shock, mitigated oxygen free radical-induced proinflammatory response, and enhanced free radical-scavenging capacity.