In a cross-sectional study of adults participating in NHANES from 2007 to 2010 the relationship between severity of DM and kidney stones was researched.14 Even when variables such as age, gender, ethnicity and BMI were equilibrated, from the point of view of HbA1c, fasting blood sugar and fasting blood insulin, there was no correlation found between severity of diabetes and presence of stones. This evidence concerns the gene INS and nephrolithiasis.