There were 6 significantly enriched pathways (Fisher Exact Probability Test, p < 0.05, Supplementary Table S7), including Adipocytokine signaling pathway, Insulin signaling pathway, Hypertrophic cardiomyopathy (HCM), Bacterial invasion of epithelial cells, Viral carcinogenesis, and Phagosome. Here, INS is linked to hypertrophic cardiomyopathy.