Moreover, as helminth infections are known to induce markers associated with M2 in helminth infections (Harn et al., 2009; Jenkins and Allen, 2010; Mishra et al., 2010), Pol-II occupancy was examined at the promoter regions of Arginase-1 (a signature marker of M2 activation phenotype). The gene discussed is ARG1; the disease is helminthiasis.