Kaplan-Meier plots showed a significant association between increased expression of ELK1, CDK4, MMP2, AURKβ, FRA, MYB, JUND, BIRC5, AKT2, SELE, TNFα (Additional file 3: Figure S3), NOS3, ESR1, KRTAP1-1, MMP3, MMP9, NF2, CXCR4, ADAMTS1, VEGF, CD54, EGFR, and AKT1 (Additional file 4: Figure 4) and poor OS in patients with neuroblastoma. This evidence concerns the gene AKT2 and neuroblastoma.