Furthermore, HIF2α has been associated with tumour-promoting properties in different types of tumours (Bangoura et al., 2007; Chiavarina et al., 2012; Holmquist-Mengelbier et al., 2006; Noguera et al., 2009; Raval et al., 2005; Scrideli et al., 2007). Here, EPAS1 is linked to neoplasm.