Kaplan–Meier survival analysis shows that OTUB1 expression is not correlated with clinical outcome in breast cancer patients, even though OTUB1 is a predictor for prognosis in patients with other malignancies, such as colorectal cancer.30, 31 Similarly, despite OTUB1 mRNA level being a prognostic marker for lung cancer patients, its expression has no predictive value for patients diagnosed with breast cancer. This evidence concerns the gene OTUB1 and breast cancer.