When adjusting for these variables, prediabetes did not significantly influence platelet aggregation or platelet turnover (p-values > 0.05), while platelet count remained an independent determinant of AA- and collagen-induced platelet aggregation, P-selectin and parameters of platelet turnover including IPC, IPF and MPV (p-values < 0.05). Here, SELP is linked to prediabetes syndrome.