An intervention study in a mouse model for orally induced cow’s milk allergy revealed a reduced acute allergic skin response and anaphylactic scores after dietary intervention with scGOS/lcFOS in combination with B. breve. Also enhanced whey-specific Th1 type serum IgG2a, fecal IgA and reduced mast cell degranulation was found in this study [51]. The gene discussed is CD79A; the disease is allergic disease.