Although extensive studies have been done examining the effect of AR agonists on immune response [17,23,24,31], studies examining the effect of AR agonists on immune responses have not adequately compared the effect on IFN-γ-producing (or Th1) and IL-17-producing (Th17) autoimmune responses, the major autoreactive T cells pathogenic to autoimmune diseases [4–8]. The gene discussed is IFNG; the disease is autoimmune disease.