CRP and tuberculosis: Coussens et al. found that 95 patients who were treated for tuberculosis and received additional vitamin D supplementation had a faster drop in CRP levels than those who received placebo.[10] In a small study of 54 subjects by Timms et al. there was a decrease in CRP after one year of vitamin D supplementation, but the study was unblinded and included severely vitamin D deficient subjects (25-hydroxyvitamin D <11 ng/ml or <27 nmol/l) only.[11] Chen et al. performed a meta-analysis of randomized controlled trials that investigated the effect of vitamin D on high-sensitive C-reactive protein.