We also found that the DICER1 rs3742330 and XPO5 rs11077 genotypes were not associated with the risk of age, gender, hypertension, DM, tumor site, tumor size, lymph node invasion, HTN and folate, suggesting that these SNPs might not modulate the susceptibility to CRC in the Korean population. This evidence concerns the gene XPO5 and colorectal carcinoma.