RAN and colorectal carcinoma: Furthermore, the RAN rs14035 CC genotype was linked with decreased risk of CRC in subjects with < 5-cm tumors (AOR = 0.654; 95% CI, 0.437–0.978; P = 0.039), homocysteine levels lower than 12.97 μmol/l (AOR = 0.637; 95% CI, 0.453–0.896; P = 0.01), and folate levels higher than 3.72 ng/ml (AOR = 0.630; 95% CI, 0.447–0.888; P = 0.008) (Table 7).