Although our study’s design does not allow for the deduction of functional conclusions on RelB effects on NSCLC cell proliferation, a recent study of head and neck squamous carcinomas revealed that IKKα, cooperatively with IKKβ, promotes cellular growth as well as nuclear RelB translocation in this tumor type, suggesting possible pro-tumor effects for RelB [40]. This evidence concerns the gene IKBKB and neoplasm.