PLIN2 and hydrops fetalis: In both genetic backgrounds, HF feeding for 4 days resulted in loss of Bacteroidetes (Plin2-null: 51% vs. 33.4% RA for chow vs. HF, p = 0.004; WT: 47.7% vs. 31.8% RA, p = 0.009; Fig 4A) compared with chow-fed animals.