TLR4 and cystic fibrosis: When the mRNA levels of TLR4, IL-6R and ADIPOR1 were analyzed in the offspring’s RET, we observed an IL-6R gene expression increased in the CF (+52.6%; p<0.05), T (+62.6%; p<0.01) and TF (+86.5%; p<0.001) groups compared with C group (Fig 4B).