Although only pups from the CF group showed elevated serum endotoxemia in a previous study [24], in this study, the 21-d-old offspring of the TF group presented with higher p-NFκB p65 protein levels in the liver (Fig 3D) and an increased serum concentration of TNF-α (Fig 1). The gene discussed is NFKB1; the disease is serum lipopolysaccharide activity.