Moreover, splicing factors for the glycolytic genes including hnrnpa, ptbp1a, ptbp1b and sfrs3b were all further up-regulated in the Myc/xmrk tumors compared with the xmrk tumor, whereas no significant change was observed in theMyctumors (Fig 6B), indicating potentially different splicing activities in these different types of tumors. Here, MYC is linked to neoplasm.