The ex vivo capacity of HIV-specific CD8+ T cells to suppress HIV-1 infection was similar in the ImmP, the VirP and the non-progressor HICs groups (median [IQR] log p24 decrease: 1.38 [0.52–2.80], 1.65 [0.39–2.99] and 1.18 [0.39–3.06], respectively). This evidence concerns the gene CD8A and HIV-1 infection.