NNT and metabolic dysfunction-associated steatotic liver disease: Interestingly, the HF-induced NAFLD that develops in the C57BL/6J was previously attributed, in part, to the spontaneous mutation in the Nnt [39, 43]; however, the data demonstrate that the C57BL/6N mice, with a functional Nnt, develop more severe NAFLD in response to HF diet feeding.