Determination of genes involved in hepatic metabolism and inflammation revealed that the C57BL/6N mice on the HF diet had altered metabolic processes, including the upregulation of glucose uptake (Slc2a2), triglyceride storage (Fasn and Srebp1c) and adipogenesis (Ppara), as well as antioxidant capacity (Gpx1) (Table 4). Here, SREBF1 is linked to hydrops fetalis.