MYD88 and splenic marginal zone lymphoma: A mutation in the MYD88 gene is present in over 90 % of lymphoplasmacytic lymphomas (LPLs) and since this entity is sometimes difficult to separate from MZ Martinez-Lopez et al. [17] investigated lymphoma samples from 19 patients with LPL, 88 patients with SMZL, 8 patients with nodal (N)MZL and 21 patients with extranodal (EN)MZL.