IFNL3 and chronic hepatitis C virus infection: In the past years, genetic studies have identified several single nucleotide polymorphisms (SNPs) (rs12979860, rs12980275, and rs8099917) around the IL-28B (interleukin-28B and interferon λ3) gene, which are strongly associated with sustained viral response to PEG-IFN and RBV treatment for chronic hepatitis C [6–8].