Since human orthologues of mouse HuB, HuC, HuD, Nova1 and Eno2 genes contain readily discernable AREs and TTP is often downregulated in tumours27, 55, 56, it will be interesting to examine whether ectopic expression of HuB/C/D, Nova1 and other NS-specific antigens in cancer cells might be triggered by aberrantly low TTP levels. The gene discussed is NOVA1; the disease is cancer.