Tumor VEGF, subtype and residual disease retained their independent significance in multivariate analysis, too (VEGF: HR = 0.19; 95% CI, 0.04-0.77; p:0.021; tumor subtype: HR = 0.10; 95% CI, 0.01-0.60; p:0.012; residual tumor: HR = 0.13; 95% CI, 0.03-0.56; p:0.007). This evidence concerns the gene VEGFA and neoplasm.