In contrast, Simon et al. found that poor survival was restricted to patients without the variant rs2853669 C-allele in GBM, [34] while in bladder cancer Rachakonda et al. (2013) have shown that the presence of the variant rs2853669 C-allele was beneficial in mutant and detrimental in a wild type TERT promoter background [13]. This evidence concerns the gene TERT and urinary bladder cancer.