Multivariate analysis revealed that the factors associated with steatosis in overweight CHC patients included age (OR/CI:1.023/1.001–1.045, P = 0.04) and diabetes (OR/CI:2.201/1.055–3.875, P = 0.03), but not PNPLA3 rs738409 genotype variants (Table 4). This evidence concerns the gene PNPLA3 and diabetes mellitus.