The proportions of PNPLA3 rs738409 GG genotype carriage were 7.8% (44/563), 15.8% (58/367) and 19.3% (17/88) in patients with no (liver fat content <5%), mild (5–33%) and moderate/severe (>66%) hepatic steatosis, respectively (trend P < 0.001). The gene discussed is PNPLA3; the disease is fatty liver disease.