MET and cancer: To investigate cell proliferation effects of c-MET inhibition by INC280, we tested the proliferation rates of untreated OVCAR3, SKOV3 and CaOV3 cancer cells, as well as the normal ovarian surface epithelium HOSE 6.3 cells, with HGF, HGF + INC280, and INC280 treatments (Fig. 2).