IHC analyses revealed robust expression of FGF1 in regions of irregular lung architecture particular to IPF, including: basal cell sheets or basal cells of hyperplastic bronchioles (Fig. 4a and b) and SMA+/Fascin + myofibroblasts of fibroblastic foci, and areas of thickened bronchial epithelium. The gene discussed is SMN1; the disease is idiopathic pulmonary fibrosis.